PARC/CCL18 is Associated with Inflammation, Emphysema Severity and Application of Inhaled Corticosteroids in Hospitalized COPD Patients
نویسندگان
چکیده
منابع مشابه
Inhaled corticosteroids in COPD
C hronic obstructive pulmonary disease (COPD) is arguably the most common chronic disease of the lungs at present and, by 2020, it will be the third leading cause of death worldwide. COPD is associated with a relentless decline in forced expiratory volume in 1 second (FEV1) and, in the later stages, the condition progresses to pulmonary hypertension and hypoxic respiratory failure. Few interven...
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The importance of presenting absolute cell numbers when counting cells in biological samples is illustrated by the potentially misleading interpretation of data in the paper by Marco Confalonieri and colleagues. The authors concluded that, in addition to reduced sputum neutrophilia, the number of sputum macrophages increased significantly following treatment with inhaled beclomethasone dipropio...
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It is 18 years since I last used the famous biblical phrase “through a glass darkly” to describe our uncertainties about the use of inhaled corticosteroids (ICS) in chronic obstructive pulmonary disease (COPD) patients [1]. Subsequently, an enormous amount of research has been undertaken, which has clarified the role of ICS in clinical management [2]. There is general agreement that these drugs...
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BACKGROUND Whether the use of inhaled corticosteroids (ICSs) in patients with COPD can protect from osteoporosis remains undetermined. The aim of this study is to assess the incidence of osteoporosis in patients with COPD with ICS use and without. PATIENTS AND METHODS This is a retrospective cohort and population-based study in which we extracted newly diagnosed female patients with COPD betw...
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In the past few years, treatment with inhaled corticosteroids has become increasingly important in asthma [1, 2]. It appears that inflammation of the airway wall is a major pathophysiological mechanism underlying asthma [3], and perhaps also chronic obstructive pulmonary disease (COPD) [4]. Some long-term studies in asthmatic patients over 1 and 2 yrs have shown that maintenance treatment with ...
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ژورنال
عنوان ژورنال: International Journal of Chronic Obstructive Pulmonary Disease
سال: 2021
ISSN: 1178-2005
DOI: 10.2147/copd.s304488